Giovanni Pisani of Venice Patrican of Venice, Cr: Duke de Candie., with issue.

1. Domenico Pisani, Signor de Santorin, married (1) Florenza Crispo, married (2) 1489 to NN Buono, with issue.

1.1. Jacopo Pisani.

1.2. Francesco Pisani.

1.3. Ottavio Pisani., (d. 1553), married with issue.

1.3.1. Jacopo Pisani.

1.3.2. Domenico Pisani, died. 1553.

1.3.3. Michele Pisani. (c. 1559)

2. Bernardo Pisani, with issue.

2.1. Gian Luigi Pisani, Signor di Zia, (r. 1541-66), married to Catherine Crispo, heiress of Zia, with issue.

2.1.1. Magnico Giovanni Pisani of Crete., settled in Malta (c. 1520).

2.1.1.1. Nicola Pisano, (c1520),  married to Margarita NN, with issue.

2.1.1.1. Romana Pisani, married to Giuseppe Dingli.

2.1.1.2. Agostino Pisani, married to Caterina NN., with issue.

2.1.1.2.1. Margaret Pisani, married (1) to Demetri Xerri., married (2) 1545 to Geronimo Catania.

2.1.1.2.2. Giovanni Maria Pisani, married to Antonia N., with issue.

2.1.1.2.2.1. Gioannella Pisani, married 1627 to Domenico Attard.

2.1.1.2.3. Agata Pisani, married 1586 to Pietro Xeberras.

2.1.1.2.4. Giovanna Pisani, married 1559 to Andrea Vella.

2.1.1.2.5. Domenico Pisani, married 1600 to Marietta Mifsud., with issue.

2.1.1.2.5.1. Antonio Pisani, married 1640 to Imperia Grima, with issue.

2.1.1.2.5.1.1. Domenico Pisani, married 1672 to Caterina Agius., with issue.

2.1.1.2.5.1.1.1. Imperia Pisani, married 1692 to Bartolomeo Gilestri.

2.1.1.2.5.1.2. Agata Pisani, married 1703 to Giovanni Camilleri.

2.1.1.3. Demetrio Pisani, married (1) 1568 to Paola Zarb, married (2) 1580 to Paola Dingli, with issue.

2.1.1.3.1. (First Marriage) Vincenza Pisani, married to Antonio Cilia.

2.1.1.3.2. Nicola Pisani, married to Caterina NN, with issue.

2.1.1.3.2.1. Gio Paolo Pisani, married 1638 to Isabella Vella.

2.1.1.3.2.2. Domenico Pisani, married 1630 to Argentina Zimech.

2.1.1.3.2.3. Gioannella Pisani, married (1) 1636 to Michele d'Argumento, married (2) 1646 to Crispino N.

2.1.1.3.2.4. Grazia Pisani, married 1629 to Niccolo Cachia.

2.1.1.3.2.5. Francesco Pisani., married to Maria N., with issue.

2.1.1.3.2.5.1. Domenica Pisani, married 1714 to Lutio Cortis.

2.1.1.3.3. Giovanni Pisani.

2.1.1.3.4. (First Marriage) Lazzaro Pisani, married 1588 to Domenica Frendo, with issue.

2.1.1.3.4.1. Domenico Pisani of Attard., married 1638 to Angelica Micallef, with issue.

2.1.1.3.4.1.1. Alessio Pisani., married 1679 at Valletta to Barbara Mamo, with issue.

2.1.1.3.4.1.1.1. Benedetto Pisani, married 1711 to Teresa Magri., with issue. (Barons of Frigenuini)

2.1.1.3.4.1.1.2. Anna Maria Pisani., married 1711 to Gasparo ….

2.1.1.3.4.1.1.3. Angelica Pisani, married 1711 to Fabrizio Grima.

2.1.1.3.4.1.1.4. Magco Giuseppe Pisani, married 1727 to Caterina Cesal., with issue.

2.1.1.3.4.1.1.4.1. Domenica Pisani.

2.1.1.3.4.1.1.4.2. Leonora Pisani.

2.1.1.3.4.1.1.4.3. Anna Maria Pisani.

2.1.1.3.4.1.1.4.4. Alessio Pisani, married (1) 1757 Valletta to Caterina Agius, married (2)1760 to Laura de Ribera., married (3) to Domitilla Bezzina, with issue.

2.1.1.3.4.1.1.4.4.1. (Second Marriage) Benedetto Pisani (1763-), married to Giuseppa Bonici Gualteri.

2.1.1.3.4.1.1.4.4.2. Christo Pisani, (1765-), married Francesca Ciantar Paleologo.

2.1.1.3.4.1.1.4.4.3. Edgar Pisani, (1769-), married Grazuilla Azopardi.

2.1.1.3.4.1.1.4.4.4. Eleanora Pisani, (1772-).

2.1.1.3.4.1.1.4.4.3. (Third Marriage) Lorenzo Pisani, married 1825 Valletta to Maria Bugeja.

2.1.1.3.4.1.1.4.4.4. Dr Salvatore Pisani JUD, married 1830 Valletta to Maria Carmela Caruana.

2.1.1.3.4.1.2. Salvatore Pisani, married 1702 to Barbara de Guiliana.

2.1.1.3.4.1.3. Giuseppe Pisani, married at Matrice Gozo to Anna Galea., with issue.

2.1.1.3.4.1.3.1. Maria Pisani, married 1739 Matrice Gozo to Carlo Xeberras.

2.1.1.3.4.1.4. Barbara Pisani, married to Francesco Busuttil.

2.1.1.3.4.2. Andrea Pisani, married 1683 at Matrice Gozo to Domenica NN, with issue.

2.1.1.3.4.2.1. Barbara Pisani, married 1706 Matrice Gozo to Paolo Bonici.

2.1.1.3.4.3. Filippo Pisani, married to Natalie NN.

2.1.1.3.4.4. Maria Pisani, married 1680 Xeuchia Gozo to Ignazio Galea.

2.1.1.3.4.5. Gio Maria Pisani, married 1674 Matrice Gozo to Caterina Azzopardi, with issue.

2.1.1.3.4.5.1. Grazia Pisani, married 1706 at Xeuchia Gozo to Gio Maria Bezzina.

2.1.1.3.4.6. Giuseppe Pisani, married 1677 Valletta to Anna Maria Russiotta, with issue.

2.1.1.3.4.6.1. Alticunda Maria Pisani, married 1707 Valletta to Paolo Marcoviz.

2.1.1.3.4.7. Margareta Pisani, married 1622 to Domenico Galdies.

2.1.1.4. Paola Pisani, married 1545 to Andrea Greco Ferraro of Gozo.

2.1.1.5. Simone Pisani, married 1538 to Paola Zammit.

2.1.2. Imperia Pisani, married 1532 to Francesco Axisa.

2.1.3. Giovanni Pisani, married 1538 to Giovanna Mangion, with issue.

2.1.3.1. Salvatore Pisani, married 1572 to Giovanna Seichel, with issue.

2.1.3.1.1. Francesca Pisani, married 1600 to Domenico Buttigieg.

2.1.3.1.2. Paolina Pisani, married 1603 to Giovanna Bonnici.

2.1.3.1.3. Agata Pisani, married 1614 to Gio Martino Agius of Gozo.

2.1.3.1.4. Alonsica Pisani, married 1616 to Gregorio NN.

2.1.3.2. Matteolo Pisani, married 1565 to Agata Hachum.

2.1.3.3. Giovanni Pisani, Arbitante of Virtu, married to Caterina.., with issue.

2.1.3.3.1. Maddalena Pisani, married 1576 to Pasquale Tanti.

2.1.3.3.2. Giovannella Pisani, married 1590 to Giovanni Cachia.

2.1.3.3.3. (illegitimate) Giuseppe Pisani, Arbitante of Virtu. (Testo: 1600).

2.1.4. Pietro Pisani, married 1549 to Caterina Vassallo, (d/o Stefano), with issue.

2.1.4.1. Marietta Pisani, married 1572 to Giorgio Bonnici.

2.1.4.2. Michele Pisani, married 1589 to Marietta Cumbo, (d/o Paolo and Agnese)., with issue.

2.1.4.2.1. Caterina Pisani, married 1642 to Mro Alonso Bonnici.

2.1.4.2.2. Valenzia Pisani, married 1639 to Stefano Attard.

2.1.4.2.3. Angelica Pisani, married 1626 to Mro Domenico Mangion.

2.1.4.2.4. Anna Pisani, married 1619 to Michele Catania.

2.1.4.2.5. Ambrosio Pisani, married 1623 to Grazia Sammut, with issue.

2.1.4.2.5.1. Petronilla Pisani, married 1647 to Filippo Muscat.

2.1.4.2.5.2. Michele Pisani, married 1660 to Petronilla Idoneo., with issue.

2.1.4.2.5.2.1. Ambrosio Pisani, married 1704 to Cristina (illegitimate daughter of Knights).

2.1.4.2.5.2.2. Gaspare Pisani, married 1707 to Cesarea Borg, with issue.

2.1.4.2.5.2.2.1. Michele Pisani, married 1731 to Evangelista Mifsud.

2.1.4.2.5.2.2.2. Maria Pisani, married 1741 to Giovanni Grech.

2.1.4.2.5.2.2.3. Caterina Pisani, married 1730 to Giuseppe Mifsud.

2.1.4.2.5.2.3. Vittorio Pisani, married 1702 to Maria Farrugia., with issue.

2.1.4.2.5.2.3.1. Petronilla Pisani, married 1740 to Salvatore Borg.

2.1.4.2.5.2.3.2. Filippo Pisani, married 1726 to Rosa Sammut.

2.1.4.2.5.2.4. Maddalena Pisani, married (1) to Domenico Sammut., married (2) 1714 to Bartolomeo Barbara.

2.1.4.2.6. Bernardina Pisani, married 1635 to Salvo de Amato.

2.1.4.3. Giovanni Pisani, married 1577 to Paoluccia Attard, with issue.

2.1.4.3.1. Pasquale Pisani, married 1600 to Grazia Ross-Burlo, with issue.

2.1.4.3.1.1. Gio Batta Pisani, married 1641 to Caterina Piantanida.

2.1.4.3.2. Isabella Pisani, married 1611 to Benedetto Mangion.

2.1.5. Paolo Pisani, married to Antonia N, with issue.

2.1.5.1. Giorgio Pisani, married 1577 to Caterina Vella.

2.1.5.2. Caterina Pisani, married 1605 to Pietro Xuereb.

2.1.5.3. Pasquale Pisani, married 1603 to Gioannella Debono, with issue.

2.1.5.3.1. Maria Pisani, married 1642 to Giovanni Dalli.

2.1.5.3.2. Mario Pisani, married 1630 to Laurea Vassallo, with issue.

2.1.5.3.2.1. Domenica Pisani, married 1680 to Mro Mario Dimech.

2.1.5.3.2.2. Giovanna Pisani, married 1661 to Paolo Pisci.

2.1.5.3.2.3. Andrea Pisani, married 1663 to Mattia Zammit., with issue.

2.1.5.3.2.3.1. Giuseppe Pisani, married (1) 1695 to Paolina Catania, married (2) 1723 to Margherita Seichel.

2.1.5.3.2.3.2. Generosa Pisani, married 1690 to Gaetano Debono.

2.1.5.3.2.4. Giovanni Pisani, married 1660 to Maria di San Severino dei Marchesi di Caiazzo., with issue.

2.1.5.3.2.4.1. Tomaso Pisani, married 1678 to Caterina Busuttil, with issue.

2.1.5.3.2.4.1.1. Giovanni Maria Pisani, married 1706 to Maria Muscat, with issue.

2.1.5.3.2.4.1.1.1. Domenica Pisani, married 1731 to Giovanni Borg.

2.1.5.3.2.4.1.1.2. Michele Pisani, married 1732 to Grazia Attard.

2.1.5.3.2.4.1.2. Giovanni Pisani, married to Caterina Grima, with issue.

2.1.5.3.2.4.1.2.1. Giovanna Pisani, married 1723 to Ignazio Debono.

2.1.5.3.2.4.1.2.2. Giuseppe Pisani, married 1719 to Lorenza Fenech, with issue.

2.1.5.3.2.4.1.2.2.1. Caterina Pisani, married 1746 to Domenico Fenech.

2.1.5.3.2.4.1.2.3. Giovanni Maria Pisani, married 1717 to Anna Grech.

2.1.5.3.2.4.1.3. Salvatore Pisani, married 1690 to Maruzza Mifsud., with issue.

2.1.5.3.2.4.1.3.1. Graziulla Pisani, married 1726 to Leonardo Attard.

2.1.5.3.2.4.1.3.2. Giovannella Pisani, married 1721 to Michele Zammit.

2.1.5.3.2.4.1.3.3. Maria Pisani, married 1734 to Marino Zammit.

2.1.5.3.2.4.1.3.4. Domenica Pisani, married 1743 to Giuseppe Mifsud.

2.1.5.3.2.4.2. Giovanni Maria Pisani, married 1683 to Paolina Zahra.

2.1.5.3.2.4.3. Agostino Pisani, married 1683 to Valenza Micallef., with issue.

2.1.5.3.2.4.3.1. Domenica Pisani, married 1699 to Giacomo Cauchi.

2.1.5.3.2.4.3.2. Maria Pisani, married 1691 to Gio Poalo Sammut.

2.1.5.3.2.4.3.3. Pietro Pisani, married 1703 to Prudenza Debono., with issue.

2.1.5.3.2.4.3.3.1. Maria Pisani, married 1736 to Giuseppe Muscat.

2.1.5.3.3. Paolina Pisani, married 1633 to Tomaso Chircop.

2.1.5.4. Geronima Pisani, married 1605 to Domenico Zimech.

2.1.5.5. Domenico Pisani, married 1609 Attard Malta to Imperia Zammit, with issue.

2.1.5.5.1. Paolina Pisani, married to Gioacchino Pcich of France.

2.1.5.5.2. Giovanella Pisani., married (1) Pietro Surtori., married (2) 1646 to Geronimo Mifsud.

2.1.5.5.3. Girolamo Pisani, married 1634 to Barbara Portelli, with issue.

2.1.5.5.3.1. Claudio Pisani, married to Laura NN, with issue.

2.1.5.5.3.1.1. Imperia Pisani, married to Antonio Bonello.

2.1.5.5.4. Mco. Simone Pisani, married 1642 Matrice Gozo to Barbara Gambin, with issue.

2.1.1.5. Agnese Pisani, married 1570 to Mariano Vella.

3. Nicolas Pisani, married with issue.

3.1. Alexandre Pisani, Signor d'Antiparos, married 1508 to Adriana Crispo.